Your One Stop Source for Cell-Adjuvant-loaded NP (CALNP) Conjugates

To provide best-in-class CALNP development services, Creative Biolabs brings together the most renowned cell engineering experts and long-term experience in cell surfce modification. Don't miss the opportunity to enter the clinic by working with service providers who provide the strongest cell therapy tools on the market!

Design

Cell line and NP design

Cell Lines

Creative Biolabs provides a variety of the industry-grade cells lines to meet your cell-related research needs. Usinf strict quality control testing, all of our cell lines are free of contaminiaton (e.g., mycoplasma), and undesired foreign factors such as fungi, viruses. In addition, our comprehensive cell portfolio is also ideal for use in clinical translation. Instrumentation platforms from cell separation, flow cytometry, to closed-system cell culture make automated processing at your fingertips. Contact us to discover how our solutions can advance your cell-related research.

Available cell lines

Immmune Cells	Stem Cells	Disease State Cells
T cells	Embryonic & Induced Pluripotent Stem Cells	Bone Marrow Mononuclear Cells (BMMCs)
B cells	Hematopoietic Stem Cells	Rheumatoid Arthritis and Osteoarthritis Fibroblasts
NK cells	Mesenchymal Stem Cells	Lung Bronchial Epithelial Cells Hepatocytes
Dendritic cells	Neural Stem Cells	Hepatocytes
Monocytes	Cancer Stem Cells	Breast Cancer Cells
Neutrophils	...	Hematopoietic Malignancies Cells
...		Renal Cells
		...

NP design and synthesis

Nanoparticles have many applications in biology and medicine and are used as biosensors, cell probes, and drug delivery vehicles. In order to achieve these specific applications of nanoparticles, it is necessary to have the ability to design the shape, size, and modify of the surface of NPs.

Creative Biolabs has extensive expertise in the design and synthesis of adjuvant-loaded NP. We provide high-quality customized NP design services and peptide synthesis services for research, diagnostic, pre-clinical and commercial applications.

Customization Capabilities:

Composition	A variety of metals, oxides, semiconductors and polymer nanomaterials are avalible. We also provide assistance with existing protocols for process optimization, scale-up and cGMP-compliant manufacturing.
Size	We can produce a variety of particle sizes and other sizes can be customized as required. We can also produce polymers up to 1 µm in size, oxide particles and core / shell structures.
Surface	Our standard nanoparticles have a variety of available anionic and cationic end-capping ligands. In addition, we can manufacture nanomaterials with specific functional groups, polymers, and biomolecules.
Concentration	We have developed techniques for processing and stabilizing high-concentration particles. UV-visible spectroscopy and ICP mass spectrometry are used to accurately measure material concentration and extinction coefficient.

Conjugation

"One-Step in Minutes"

Based on our CellFace™ conjugate technology platform, we utilize fucosyltransferases (Fuc T) to transfer NP to the surface of living cells in minutes. This one-step approach developed by scientist team is a fast, simple, and cost-effective technique for cell surface engineering. Using this method, any adjuvant-loaded NPs can be introduced to the cell surface without genetic modification of the host cells.