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Control of Cell-Cell Interactions

Active in the development of cell surface conjugates, Creative Biolabs is considered a leading global provider to offer cell surface engineering for the control of cell-cell interaction.

Cell Surface Conjugates for Control of Cell-Cell Interaction

Dynamic cell-cell interactions are imperative for correct cell behavior and cell functions. Previous studies have demonstrated that cell membrane and various cell surface ligands may be associated with other cells or with extracellular materials, regulating extracellular communication. Thus, it is worth considering the biomolecular composition of the membrane and how these molecules are arranged. More recently, many research groups have been focused their work on the engineering of the cell surface with different strategies such as biological, chemical, or physical methods for the control of ligand presentation on cell surfaces to modulate cell functions and control cell-cell and cell-microenvironment interactions. Such modulation of cell-cell interactions would benefit fundamental cell-behavioral studies, allow unprecedented control of cell behavior, and provide a synthetic biological method for the design of cell-based therapy.

Control of cell attachment. Fig.1 Control of cell attachment. (Teramura, 2010)

Control of cell-cell reversible interactions. Fig.2 Control of cell-cell reversible interactions. (Shi, 2016)

Remote control of tissue interactions. Fig.3 Remote control of tissue interactions. (Luo, 2014)

At Creative Biolabs, we offer one-stop solutions for cell surface conjugate development and characterization to meet your specific project demands to control cell-cell interaction. If you want to know more detailed information, please feel free to contact our experts.

References

  1. Teramura, Y.; et al. Control of cell attachment through polyDNA hybridization. Biomaterials. 2010, 31(8), pp.2229-2235.
  2. Luo, W.; et al. Remote control of tissue interactions via engineered photo-switchable cell surfaces. Scientific reports. 2014, 4(1), pp.1-8.
  3. Shi, P.; et al. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications. 2016, 7(1), pp.1-9.

All services are only provided for research purposes and Not for clinical use.

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